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Dr. Silke Lohan, Dipl.-Biol.

Postdoktorandin in der Arbeitsgruppe PD Dr. Martina Meinke (TP B01)
Klinik für Dermatologie, Venerologie und Allergologie
Charité Universitätsmedizin Berlin, Arbeitsgruppe PD Dr. M. Meinke

Kontakt:
Tel.: +49 (030) 450 518 244
Email: silke.lohan (at) charite.de

Center of Experimental and Applied Cutaneous Physiology (CCP)


Teilprojekt B01:
EPR spectroscopic investigations on drug delivery and release of nanocarriers into cutaneous cells and excised skin


SFB 1112-Publikationen:

Giulbudagian M, Hönzke S, Bergueiro J, Isik D, Schumacher F, Saeidpour S, Lohan SB, Meinke MC, Teutloff C, Schäfer-Korting M, Yealland G, Kleuser B, Hedtrich S, Calderón M 2017. Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels. Accepted for publication in: Nanoscale DOI 10.1039/C7NR04480A

Jager J, Obst K, Lohan SB, Voktorov J, Staufenbiel S, Renz H, Unbehauen M, Haag R, Hedtrich S, Teutloff C, Meinke MC, Danker K, Dommisch H 2017. Characterization of hyperbranched core-multishell nanocarriers as an innovative drug delivery system for the application at the oral mucosa. J Periodontal Res. Epub ahead of print. DOI 10.1111/jre.12487

Lohan SB, Ahlberg S, Mensch A, Höppe D, Giulbudagian M, Calderón M, Grether-Beck S, Krutmann J, Lademann J, Meinke MC 2017. EPR technology as sensitive method for oxidative stress detection in primary and secondary keratinocytes induced by two selected nanoparticles. Cell Biochem Biophys DOI 10.1007/s12013-017-0823-4

Lohan SB, Saeidpour S, Solik A, Schanzer S, Richter H, Dong P, Darvin ME, Bodmeier R, Patzelt A, Zoubari G, Unbehauen M, Haag R, Lademann J, Teutloff C, Bittl R, Meinke MC 2017. Investigation of the cutaneous penetration behavior of dexamethasone loaded to nano-sized lipid particles by EPR spectroscopy, and confocal Raman and Laser scanning microscopy. Accepted for publication in  Eur J Pharm Biopharm, in press, DOI 10.1016/j.ejpb.2016.12.018

Saeidpour S, Lohan SB, Solik A, Paul V, Bodmeier R, Zoubari G, Unbehauen M, Haag R, Bittl R, Meinke MC, Teutloff C 2017. Drug distribution in nanostructured lipid particles. Eur J Pharm Biopharm, in press, DOI 10.1016/j.ejpb.2016.10.008 (Epub ahead of print)

Saeidpour S, Lohan SB, Anske M, Unbehauen M, Fleige E, Haag R, Meinke MC, Bittl R, Teutloff C 2017. Localization of dexamethasone within dendritic core-multishell (CMS) nanoparticles and skin penetration properties studied by multi-frequency electron paramagnetic resonance spectroscopy (EPR). Eur J Pharm Biopharm, in press, DOI 10.1016/j.ejpb.2016.10.001 (Epub ahead of print)

Gerecke C, Edlich A, Giulbudagian M, Schumacher F, Zhang N, Said A, Yealland G, Lohan SB, Neumann F, Meinke MC, Ma N, Calderón M, Hedtrich S, Schäfer-Korting M, Kleuser B 2017. Biocompatibility and characterization of polyglycerol-based thermoresponsivenanogels designed as novel drug-delivery systems and their intracellularlocalization in keratinocytes. Nanotoxicology DOI 10.1080/17435390.2017.1292371 (online publication, 11 pages)

Lohan SB, Icken N, Teutloff C, Saeidpour S, Bittl R, Lademann J, Fleige E, Haag R, Haag SF, Meinke MC 2016. Investigation of cutaneous penetration properties of stearic acid loaded to dendritic core-mulit-shell (CMS) nanocarriers. Int J Pharm 501:271-277 DOI 10.1016/j.ijpharm.2016.02.004

Lohan SB, Bauersachs S, Ahlberg S, Baisaeng N, Keck CM, Müller RH, Witte E, Wolk K, Hackbarth S, Röder B, Lademann J, Meinke MC 2015. Ultra-small lipid nanoparticles promote the penetration of coenzyme Q10 in skin cells and counteract oxidative stress. Eur J Pharm Biopharm 89:201-207 DOI 10.1016/j.ejpb.2014.12.008