Dr. Christian Gerecke, Dipl.-Biol.

Postdoktorand in der Arbeitsgruppe Prof. Dr. Burkhard Kleuser (TP Z01)
Institut für Ernährungswissenschaft
Universität Potsdam


Teilprojekt Z01:
Toxicity of native and drug-loaded nanocarriers.

SFB 1112-Publikationen:

Balzus B, Sahle FF, Hönzke S, Gerecke C, Schumacher F, Hedtrich S, Kleuser B, Bodmeier R 2017. Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium. Accepted for publication in: Eur J Pharm Biopharm DOI 10.1016/j.ejpb.2017.02.001

Gerecke C, Edlich A, Giulbudagian M, Schumacher F, Zhang N, Said A, Yealland G, Lohan SB, Neumann F, Meinke MC, Ma N, Calderón M, Hedtrich S, Schäfer-Korting M, Kleuser B 2017. Biocompatibility and characterization of polyglycerol-based thermoresponsivenanogels designed as novel drug-delivery systems and their intracellularlocalization in keratinocytes. Nanotoxicology DOI 10.1080/17435390.2017.1292371 (online publication, 11 pages)

Edlich A, Gerecke C, Giulbudagian M, Neumann F, Hedtrich S, Schäfer-Korting M, Ma N, Calderón M, Kleuser B 2016.Specific uptake mechanisms of well-tolerated thermoresponsive polyglycerol-based nanogels in antigen-presenting cells of the skin. Accepted for publication in Eur J Pharm Biopharm, in press, DOI 10.1016/j.ejpb.2016.12.016 (24.12.2016)

Sahle FF, Balzus B, Gerecke C, Kleuser B, Bodmeier R 2016. Formulation and in vitro evaluation of polymeric enteric nanoparticles as dermal carriers with pH-dependent targeting potential. Eur J Pharm Sci 92:98-109 DOI 10.1016/j.ejps.2016.07.004 (epub ahead of print)

Zhang N, Said A, Wischke C, Kral V, Brodwolf R, Volz P, Boreham A, Gerecke C, Li W, Neffe AT, Kleuser B, Alexiev U, Lendlein A, Schäfer-Korting M 2016. Poly[acrylonitrile-co-(N-vinyl pyrrolidone)] nanoparticles - composition-dependent skin penetration enhancement of a dye probe and biocompatibility. Eur J Pharm Biopharm, in press, DOI 10.1016/j.ejpb.2016.10.019 (Epub ahead of print)

Pischon H, Radbruch M, Ostrowski A, Volz P, Gerecke C, Unbehauen M, Hönzke S, Hedtrich S, Fluhr JW, Haag R, Kleuser B, Alexiev U, Gruber AD, Mundhenk L 2016. Stratum corneum targeting by dendritic core-multishell-nanocarriers in a mouse model of psoriasis. Nanomedicine: NBM 13:317-327 DOI 10.1016/j.nano.2016.09.004

Sahle FF, Gerecke CKleuser BBodmeier R 2017. Formulation and comparative in vitro evaluation of various dexamethasone-loaded pH-sensitive polymeric nanoparticles intended for dermal applications. Int J Pharm 516:21-31 DOI 10.1016/J.ijpharm.2016.11.029

Ahlberg S, Rancan F, Epple M, Loza K, Höppe D, Lademann J, Vogt A, Kleuser B, Gerecke C, Meinke MC 2016. Comparison of different methods to study effects of silver nanoparticles on the pro- and antioxicant status of human keratinocytes and fibroblasts. Methods 109:55-63 DOI 10.1016/j.ymeth.2016.05.015

Hönzke S, Gerecke C, Elpelt A, Zhang N, Unbehauen M, Kral V, Fleige E, Paulus F, Haag R, Schäfer-Korting M, Kleuser B, Hedtrich S 2016. Tailored dendritic core-multishell nanocarriers for efficient dermal drug delivery: A systematic top-down approach from synthesis to preclinical testing. J Control Release 242:50-63. DOI 10.1016/j.jconrel.2016.06.030