SFB 1112 in Press and Media

January 2018: SFB 1112-Publication featured as  "Frontcover Highlight" in Journal "Theranostics"

Giulbudagian G, Yealland G, Hönzke S, Edlich A, Geisendörfer B, Kleuser B, Hedtrich S, Calderón M 2018. Breaking the barrier - potent anti-inflammatory activity following efficient topical delivery of etanercept using thermoresponsive nanogels. Theranostics 8:450-463 DOI 10.7150/thno.21668
Frontcover Theranostics 2018:8(2)



Oktober 2017: "Von Doktoranden für Doktoranden"
campus.leben-report on the 10th Doctoral Student Symposium of DRS doctoral studies program Biomedical Sciences
Award for best Presentation goes to SFB 1112-doctoral student Stephanie Albrecht (Project B01, Meinke group)

campus.leben, 16.10.2017, Freie Universität Berlin


Oktober 2017: SFB 1112-Publikation is voted "Paper Highlight" at the Institute of Chemistry and Biochemistry, Facultry of Biology, Chemistry, and Pharmacy, Freie Universität Berlin

Combination of Surface Charge and Size Controls the Cellular Uptake of Functionalized Graphene Sheets
Zhaoxu Tu, Katharina Achazi, Andrea Schulz, Rolf Mülhaupt, Steffen Thierbach, Eckart Rühl, Mohsen Adeli, and Rainer Haag, Adv. Funct. Mater. 2017, 27, 17018377


June 2017: Special Issue of European Journal of Pharmaceutics and Biopharmaceutics:
Nanocarriers: Architecture, Transport, and Topical Application of Drugs for Therapeutic Use

Edited by Andreas Lendlein and Eckart Rühl

European Journal of Pharmaceutics and Biopharmaceutics, 2017, Volume 116, Pages 1-164


May 2017: SFB 1112-publication is voted "Paper Highlight" at the Institute of Chemistry and Biochemistry, Facultry of Biology, Chemistry, and Pharmacy, Freie Universität Berlin

Data-based modeling of drug penetration relates human skin barrier function to the interplay of diffusivity and free-energy profiles
Robert Schulz, Kenji Yamamoto, André Klossek, Roman Flesch, Stefan Hönzke, Fiorenza Rancan, Annika Vogt, Ulrike Blume-Peytavi, Sarah Hedtrich, Monika Schäfer-Korting, Eckart Rühl, and Roland R. Netz, Proc. Natl. Acad. Sci. USA 2017, 114(14), 3631-36366

10.04.2017: ARTE-TV report on application of CMS-Nanocarriers for targeted drug delivery, Haag group/SFB 1112-Project A02

Roboter im Blut ("Robots in the blood"), ARTE-TV report by Mathilde Schnee

Since the first use of the term "nanotechnology" in 1974, research has advanced significantly. At the Institute of Chemistry and Biochemistry of Freie Universität Berlin, so-called nanocarriers were developed: tiny transporters for targeted drug delivery. As a spin-off from the university team, a start-up company is testing the new technology for skin drug delivery in cats and has been awarded the Berlin-Brandenburg Innovation Prize.

Taken from: info.arte.tv, ARTE (German only)

20.01.2017: "Gut verpackt ans Ziel - Well-wrapped on target" - European Patent on Gel Capsule issued, Haag group/SFB 1112-Project A02

Well-wrapped on target: Freie Universität Berlin has been issued a European patent for a gel capsule designed as a nanocarrier for drug delivery in the human body. The nanogel releases its susceptible drug cargo - enzymes or proteins -  directly on the desired site of action, e.g. in the environment of inflamed or tumor tissue, because altered acidic tissue pH associated with these pathologies will lead to dissolution of the nanogel 'wrap'.

The nanogel is composed of polyglycerin and can release its cargo on the target site without additional action of tensides, ultrasound or heat that are commonly used for on-site drug release from nanocarriers. Thus, the therapeutic properties of labile drug biomolecules are maintained using the patented nanogel. The nanogel capsule was invented by Rainer Haag, Professor at Institute of Chemistry and Biochemistry of Freie Universität Berlin, and Dirk Steinhilber, doctoral student with R. Haag, as well as by scientists from LMU München.

News-item Profund Innovation, Freie Universität Berlin (German only)

December 2016: SFB 1112-publication is voted "Paper Highlight" at the Institute of Chemistry and Biochemistry, Facultry of Biology, Chemistry, and Pharmacy, Freie Universität Berlin

Core-multishell nanocarriers: Transport and release of dexamethasone probed by soft X-ray spectromicroscopy
K. Yamamoto, A. Klossek, R. Flesch, T. Ohigashi, E. Fleige, F. Rancan, J. Frombach, A. Vogt, U. Blume-Peytavi, P. Schrade, S. Bachmann, R. Haag, S. Hedtrich, M. Schäfer-Korting, N. Kosugi, E. Rühl, J. Control. Release 2016, 242, 64-70


November 2016: Special Issue of Journal of Controlled Release:
International Conference on Dermal Drug Delivery by Nanocarriers, Berlin 14-16 March

Edited by Wim Hennink, Andreas Lendlein and Eckart Rühl

Journal of Controlled Release, 2016, Volume 242, Pages e1-e6, 1-148


October 2016: Dendritic Polyglycerol-Based Nanogels for Dermal Drug Delivery -  SFB 1112-research news published in Newsletter of the Controlled Release Society

The groups of Prof. Dr. Marcelo Calderón and Prof. Dr. Sarah Hedtrich present latest SFB 1112-research news in the   "Scientifically Speaking" category of the current CRS Newsletter (member only publication of the Controlled Release Society):

Dendritic polyglycerol-based nanogels for dermal drug delivery. Molina M, Witting M, Calderón M, Hedtrich S 2016. CRS Newsletter 33(4):10-12

21.09.2016: Thermogels against skin diseases and tumors  - FU Patent application at World Intellectual Property Organization, Calderón group/SFB 1112-Project A04

The group of  Prof. Calderón has developed new thermo-nanogels for the encapsulation of drugs, with a gradual drug release at the site of action. Potential fields of application for the nanogels are modern tumor therapies and topical therapy of inflammatory skin diseases such as psoriasis and atopic dermatitis. 

Newsmeldung Profund Innovation, Freie Universität Berlin (German only)

12.09.2016: "Die Gene alleine sind nicht schuld" - R.O.S.A.-Award for SFB 1112-publication on causes of Atopic Dermatitis, Distinction for Prof. Dr. Sarah Hedtrich ("Genes cannot be held responsible")

Freie Universität Berlin, Stabsstelle Presse und Kommunikation, Wissenschaft aktuell, 2016, Themen im September

Award-winning SFB 1112-publication:
Influence of Th2 cytokines on the cornified envelope, tight junction proteins and ß-defensins in filaggrin-deficient skin models. Hönzke S, Wallmeyer L, Ostrowski A, Radbruch M, Mundhenk L, Schäfer-Korting M, Hedtrich S 2015. J Invest Dermatol 136:631-639 DOI 10.1016/j.jid.2015.11.007 (19.11.2015)


August 2016: Two SFB 1112-Publications are highlighted as "Selected Publications July" (Ausgewählte Publikationen im Juli) in the German Newsletter of Charité Universitätsmedizin Berlin (Editor: GB Unternehmenskommunikation)

Nanocarriers for drug delivery into and through the skin - do existing technologies match clinical challenges?
A. Vogt, C. Wischke, A. T. Neffe, N. Ma, U. Alexiev, and A. Lendlein, J. Control. Release 2016, in press, DOI 10.1016/j.jconrel.2016.07.027 (Review)

Ethyl cellulose nanocarriers and nanocrystals differentially deliver dexamethasone into intact, tape-stripped or sodium lauryl sulfate-exposed ex vivohuman skin -assessment by intradermal microdialysis and extraction from the different skin layers.
N. Döge, S. Hönzke, F. Schumacher, B. Balzus, M. Colombo, S. Hadam, F. Rancan, U. Blume-Peytavi, M. Schäfer-Korting, A. Schindler, E. Rühl, P. Stahl Skov, M. Church, S. Hedtrich, B. Kleuser, R. Bodmeier, and A. Vogt, J Control Release 2016, in press, DOI 10.1016/j.jconrel.2016.07.009 (Epub ahead of print)

January 2016: Polymer Chemist Dr. Dirk Steinhilber (Projekt A02) is awarded "Bruno-Heck-Wissenschaftspreis der Altstipendiaten der Konrad-Adenauer-Stiftung"

Press Release, Freie Universität Berlin, Nr. 011/2016, 14.01.2016


July 2015: SFB-Publication highlighted in Annual Report of Partner Institution UVSOR Facility, National Institutes of Natural Sciences, Institute for Molecular Science, Okazaki/Japan

The recent SFB-Publication Yamamoto et al. on "Selective Probing of the Penetration of Dexamethasone into Human Skin by Soft-X-Ray Spectromicroscopy", Anal Chem 2015, 87, 6173–6179, was featured as scientific highlight in the Annual Report 2014 of UVSOR Facility, National Institutes of Natural Sciences, Institute for Molecular Science, Okazaki/Japan.

July 2015: SFB 1112-publication is voted "Paper Highlight" at the Institute of Chemistry and Biochemistry, Facultry of Biology, Chemistry, and Pharmacy, Freie Universität Berlin

Selective Probing of the Penetration of Dexamethasone into Human Skin by Soft X-ray Spectromicroscopy
K. Yamamoto, R. Flesch, T. Ohigashi, S. Hedtrich, A. Klossek, P. Patoka, G. Ulrich, S. Ahlberg, F. Rancan, A. Vogt, U. Blume-Peytavi, P. Schrade, S. Bachmann, M. Schäfer-Korting, N. Kosugi, and E. Rühl, Anal. Chem. 2015, 87(12), 6173-6179

05.05.2015: Award for Sarah Hedtrich -  Astellas Forschungspreis 2015

Prof. Dr. Sarah Hedtrich (Project C02) was awarded with the "Astellas Forschungspreis 2015"  (Astellas Research Award 2015) for her work on atopic Dermatitis.

Press Release, Freie Universität Berlin, Nr. 125/2015, 05.05.2015

15.09.2014: SFB 1112-Publication highlighted as "Back Cover" of Journal "Polymer Chemistry"

Fabrication of Thermoresponsive Nanogels by Thermo-Nanoprecipitation and in situ Encapsulation of Bioactives
M. Giulbudagian, M. Asadian-Birjand, D. Steinhilber, K. Achazi, M. A. Molina, M. Calderón, Polymer Chemistry 2014, 5, 6909-6913

August 2014: "Alle Preise gehen an den Sonderforschungsbereich "Nanocarrier" der FU Berlin" DermoTopics, Issue 1/2014 ("All Awards go to Collaborative Research Center "Nanocarriers" of Freie Universität Berlin")

Report on poster-prizes ("Hans Christian Korting-Nachwuchspreis für Dermopharmazie") awarded to members of SFB 1112 on the 18th Annual Conference of the German Dermopharmceutical Society/Gesellschaft für Dermopharmazie; DermoTopics, Issue 1/2014

April 2014: "Neues zum Thema „Haut“ - Nachwuchs ausgezeichnet"
Deutsche Apothekerzeitung Nr. 16/2014 ("News on Topic Skin - Junior Researchers awarded")

Report on on the 18th Annual Conference of the German Dermopharmceutical Society/Gesellschaft für Dermopharmazie and poster-prizes ("Hans Christian Korting-Nachwuchspreis für Dermopharmazie") awarded to members of SFB 1112; DAZ 2014, Nr. 16, S. 87 17.04.2014

January 2014: SFB 1112-publication is voted "Paper Highlight" at the Institute of Chemistry and Biochemistry, Facultry of Biology, Chemistry, and Pharmacy, Freie Universität Berlin

A Microgel Construction Kit for Bioorthogonal Encapsulation and pH-Controlled Release of Living Cells
D. Steinhilber, T. Rossow, S. Wedepohl, F. Paulus, S. Seiffert, R. Haag, Angew. Chem. Int. Ed. 2013, 52(51), 13538-13543

30.11.2013: "Forschung, die unter die Haut geht" Tagesspiegel (Berlin newspaper) supplement


01.11.2013: Impressions from Opening Ceremony of SFB 1112


01.11.2013: "Mini-Shuttle für den Medikamenten-Transport" campus.leben (Online Magazine of FU Berlin) ("Mini-Shuttle for Drug Transport")


28.10.2013: "An der Freien Universität eröffnet Sonderforschungsbereich zur Behandlung entzündlicher Hauterkrankungen" Press Release by FU Berlin on Opening Ceremony of SFB 1112
24.05.2013: "DFG richtet zwölf neue Sonderforschungsbereiche ein" Press Release of German Research Foundation (DFG)


24.05.2013: "Neuer Sonderforschungsbereich an Freier Universität Berlin - Interdisziplinäres Team erforscht neue Wege zur Behandlung entzündlicher Hauterkrankungen" Press Release by FU Berlin