Teilprojekte des SFB 1112
Teilprojekte des SFB 1112
Projektbereich A: Synthese, Wirkstoffaufnahme und Markierung von Nanocarriern | ||
|---|---|---|
| A01 | R. Bodmeier (Pharmazeutische Technologie, Institut für Pharmazie, FU Berlin) | Development of "smartNLC" and "ARTcrystals" for dermal application of drugs |
| A02 | R. Haag (Institut für Chemie und Biochemie, FU Berlin) | Polymer architectures with responsive nanocarriers for drug delivery |
| A03 | A. Lendlein/A. Neffe (Inst. für Biomaterialforschung, Helmholtz Zentrum Geesthacht, Teltow) | Drug releasing, biodegradable depsipeptide nanoparticles for dermal treatments |
| A04 | R. Haag/M. Calderón (Institut für Chemie und Biochemie, FU Berlin) | Development of pH-cleavable and thermoresponsive nanogels as nanocarriers for the transdermal triggered release of drugs |
Projektbereich B: Physikalische Diagnostik und numerische Modellierung | ||
| B01 | M. Meinke/R. Bittl (Dermatologie, Charité Berlin / (Fachbereich Physik, FU Berlin) | EPR spectroscopic investigations on drug delivery and release of nanocarriers into cutaneous cells and excised skin |
| B02 | E. Rühl (Institut für Chemie und Biochemie, FU Berlin) | Spatially and temporally resolved studies on the transport of nanocarriers and drug release in cells and skin |
| B03 | U. Alexiev (Fachbereich Physik, FU Berlin) | Characterization of transport and release properties of responsive nanocarriers by fluorescence spectroscopy and localization microscopy |
| B04 | R. Netz (Fachbereich Physik, FU Berlin) | Multiscale models for carrier-assisted drug transport through skin |
Projektbereich C: Nanopharmakologie und Dermatologie | ||
| C02 | M. Schäfer-Korting/S. Hedtrich, geb. Küchler (Institut für Pharmazie, FU Berlin) | In vitro disease models – test platform for the investigation of nanocarrier related transport, activity, and toxicity of drugs |
| C03 | L. Mundhenk/A. Gruber (Fachbereich Veterinärmedizin, FU Berlin) | Nanocarriers in the skin of mouse models: Penetration, effects of barrier dysfunctions in diseased skin and improved targeting of inflammation |
| C04 | A. Vogt/U. Blume-Peytavi (Dermatologie, Charité Berlin) | Ex vivo human skin: Impact of skin barrier function and the presence of hair follicles on nanocarrier-based anti-inflammatory therapy |
| C05 | J. Lademann (Dermatologie, Charité Berlin) | Dermal trigger parameters for drug release from nanocarriers |
Zentralprojekte | ||
| Z01 | B. Kleuser/N. Ma/M. Schäfer-Korting (Institut für Ernährungswissenschaften, U Potsdam/Inst. für Biomaterialforschung, Helmholtz Zentrum Geesthacht (Teltow)/ Institut für Pharmazie, FU Berlin) | Toxicity of native and drug-loaded nanocarriers |
| MGK | E. Rühl (Institut für Chemie und Biochemie, FU Berlin) | Integrated Research Training Group “Nanocarriers" |
| Z02 | E. Rühl (Institut für Chemie und Biochemie, FU Berlin) | Central tasks - CRC Headquarter and administration |