Assoziierte Doktorandin in der Arbeitsgruppe Prof. Dr. Sarah Hedtrich (TP C02)
Pharmakologie und Toxikologie
Institut für Pharmazie
Fachbereich Biologie, Chemie, Pharmazie
Freie Universität Berlin

Kontakt:
Tel. +49 30 838 53944
Email: katja.obst (at) fu-berlin.de

Dissertationsprojekt:

Nanoparticulate systems as potential protein carriers and their fate in a biological environment

Dissertation abgeschlossen in 11/2017.

SFB 1112-Publikationen:

Jager J, Obst K, Lohan SB, Voktorov J, Staufenbiel S, Renz H, Unbehauen M, Haag R, Hedtrich S, Teutloff C, Meinke MC, Danker K, Dommisch H 2017. Characterization of hyperbranched core-multishell nanocarriers as an innovative drug delivery system for the application at the oral mucosa. J Periodontal Res. Epub ahead of print. DOI 10.1111/jre.12487

Obst K, Yealland G, Miceli E, Dimde M, Balzus B, Weise C, Eravci M, Bodmeier R, Haag R, Calderón M, Charbaji N, Hedtrich S 2017. Protein corona formation on polymeric nanoparticles possessing porous, solid and PEG-based surfaces of varied surface charge and hydrophobicity: impact on cellular uptake, toxicity, immunogenicity and drug release properties. Biomacromolecules 18:1762-1771 DOI 10.1021/acs.biomac.7b00158

Witting M, Molina M, Obst K, Plank R, Eckl KM, Hennies HC, Calderon M, Frieß W, Hedtrich S 2015. Thermoresponsive hyperbranched polyglycerol nanogels for cutaneous drug delivery of biomacromolecules. Nanomedicine: NBM 11:1179-1187 DOI 10.1016/j.nano.2015.02.017

Witting M, Obst K, Friess W, Hedtrich S 2015. Recent Advances in Topical Delivery of Proteins and Peptides Mediated by Soft Matter Nanocarriers. Biotechnological Advances 33:1355-1369 DOI 10.1016/j.biotechadv.2015.01.010 (Review)