Doktorand in der Arbeitsgruppe Jun.-Prof. Dr. Marcelo Calderón (TP C04)
Organische Chemie
Institut für Chemie und Biochemie
Fachbereich Biologie, Chemie, Pharmazie
Freie Universität Berlin

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Dissertation eingereicht zum Thema:

Development and Adaptation of Thermoresponsive Nanogels for the Treatment of Inflammatory Skin Diseases

Erstbetreuer:                           Jun.-Prof. Dr. Marcelo Calderón

Zweitbetreuer:                          PD Dr. Annika Vogt

Drittbetreuerin/Mentorin:           Prof. Dr. Martina Meinke

Publikationen:

Giulbudagian M, Hönzke S, Bergueiro J, Isik D, Schumacher F, Saeidpour S, Lohan SB, Meinke MC, Teutloff C, Schäfer-Korting M, Yealland G, Kleuser B, Hedtrich S, Calderón M 2017. Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels. Accepted for publication in: Nanoscale DOI 10.1039/C7NR04480A

Giulbudagian M, Yealland G, Hönzke S, Edlich A, Geisendörfer B, Kleuser B, Hedtrich S, Calderón M 2018. Breaking the barrier - potent anti-inflammatory activity following efficient topical delivery of etanercept using thermoresponsive nanogels. Theranostics 8:450-463 DOI 10.7150/thno.21668

Lohan SB, Ahlberg S, Mensch A, Höppe D, Giulbudagian M, Calderón M, Grether-Beck S, Krutmann J, Lademann J, Meinke MC 2017. EPR technology as sensitive method for oxidative stress detection in primary and secondary keratinocytes induced by two selected nanoparticles. Cell Biochem Biophys DOI 10.1007/s12013-017-0823-4

Sahle FF, Giulbudagian M, Bergueiro J, Lademann J, Calderón M 2017. Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle. Nanoscale 9:172-182 DOI 10.1039/C6NR06435C

Edlich A, Gerecke C, Giulbudagian M, Neumann F, Hedtrich S, Schäfer-Korting M, Ma N, Calderón M, Kleuser B 2016.Specific uptake mechanisms of well-tolerated thermoresponsive polyglycerol-based nanogels in antigen-presenting cells of the skin. Accepted for publication in Eur J Pharm Biopharm, in press, DOI 10.1016/j.ejpb.2016.12.016 (24.12.2016)

Rancan F, Giulbudagian M, Jurisch J, Blume-Peytavi U, Calderón M, Vogt A 2016. Drug delivery across intact and disrupted skin barrier: identification of cell populations interacting with penetrated thermoresponsive nanogels. Eur J Pharm Biopharm, accepted for publication (15.11.2016)

Giulbudagian M, Rancan F, Klossek A, Yamamoto K, Jurisch J, Colombo Neto V, Schrade P, Bachmann S, Rühl E, Blume-Peytavi U, Vogt A, Calderón M 2016. Correlation between the chemical composition of thermoresponsive nanogels and their interaction with the skin barrier. J Contr Release, 243:323-332 DOI 10.1016/j.jconrel.2016.10.022

Giulbudagian M, Asadian-Birjand M, Steinhilber D, Achazi K, Molina M, Calderón M 2014. Fabrication of thermoresponsive nanogels by thermo-nanoprecipitation and in situ encapsulation of bioactives. Polym Chem 5:6909-6913 DOI 10.1039/C4PY01186D

Molina M, Giulbudagian M, Calderón M 2014. Positively Charged Thermoresponsive Nanogels for Anticancer Drug Delivery. Macromol Chem Phys 215:2414-2419 DOI 10.1002/macp.201400286