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Mathias Dimde

Doktorand in der Arbeitsgruppe Prof. Dr. Rainer Haag (TP A02)
Organische Chemie
Institut für Chemie und Biochemie
Fachbereich Biologie, Chemie, Pharmazie
Freie Universität Berlin


Dissertation eingereicht zum Thema:

Stimuli-Sensitive Nanocarriers for Diagnostic and Therapy

Erstbetreuer:                           Prof. Dr. Rainer Haag

Zweitbetreuer:                          Dr. Jens Dernedde

Drittbetreuerin:                         Prof. Dr. Beate Paulus


  1. Dimde M, Neumann F, Reisbeck F, Ehrmann S, Cuellar-Camacho JL, Steinhilber D, Ma N, Haag R 20017. Defined pH-sensitive nanogels as gene delivery platform for siRNA mediated in vitro gene silencing. Biomater Sci 5:2328-2336 DOI 10.1039/c7bm00729a
  2. Dimde M, Steinhilber DNeumann F, Li Y, Paulus FMa NHaag R 2017. Synthesis of pH-cleavable dPG-amines for gene delivery application. Macromol Biosci 17:1616-5195, DOI 10.1002/mabi.201600190
  3. Dimde M, Sahle FF, Wycisk V, Steinhilber D, Cuellar L, Licha K, Lademann J, Haag R 2017. Synthesis and validation of functional nanogels as pH-sensors in the hair follicle. Accepted for publication in: Macromol Biosci
  4. Zabihi F, Wieczorek S, Dimde M, Hedtrich S, Börner HG, Haag R 2016. Intradermal drug delivery by nanogel-peptide conjugates; specific and efficient transport of temoporfin. J Control Release, in press, DOI 10.1016/j.jconrel.2016.07.033
  5. Zhong Y, Dimde M, Stöbener D, Meng F, Deng C, Zhong Z, Haag R 2016. Micelles with sheddable dendritic polyglycerol sulfate shells show extraordinary tumor targetability and chemotherapy in vivo. ACS Appl Mater Interfaces 8:27530-27538 DOI 10.1021/adxami.6b09204
  6. Obst K, Yealland G, Miceli E, Dimde M, Balzus B, Weise C, Eravci M, Bodmeier R, Haag R, Calderón M, Charbaji N, Hedtrich S 2017. Protein corona formation on polymeric nanoparticles possessing porous, solid and PEG-based surfaces of varied surface charge and hydrophobicity: impact on cellular uptake, toxicity, immunogenicity and drug release properties. Accepted for publication in: Biomacromolecules DOI 10.1021/acs.biomac.7b00158