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Miriam Colombo

Doktorandin in der Arbeitsgruppe Prof. Dr. Roland Bodmeier (TP A01)
Pharmazeutische Technologie
Institut für Pharmazie
Freie Universität Berlin

mcolombo (at) zedat.fu-berlin.de


Formulation development of drug nanocrystals and nanoparticles for dermal delivery.

Erstbetreuer: Prof. Dr. Roland Bodmeier


  1. Colombo M, Staufenbiel S, Rühl E, Bodmeier R 2017. In situ determination of the saturation solubility of nanocrystals of poorly soluble drugs for dermal application. Int J Pharm 531:156-166 DOI 10.1016/j.ijpharm.2017.02.030
  2. Colombo M, Orthmann S, Bellini M, Staufenbiel S, Bodmeier R 2017. Influence of drug brittleness, nanomilling time, and freeze-drying on the crystallinity of poorly water-soluble drugs and its implications for solubility enhancement. Accepted for publication in: AAPS PharmSciTech DOI 10.1208/s12249-017-0722-4 (Epub ahead of print)
  3. Balzus B, Colombo M, Sahle FF, Zoubari G, Staufenbiel S, Bodmeier R 2016. Comparison of different in vitro release methods used to investigate nanocarriers intended for dermal application. Int J Pharm 513:247-254 DOI 10.1016/jijpharm.2016.09.33 (Epub ahead of print)
  4. Döge N, Hönzke S, Schumacher F, Balzus B, Colombo M, Hadam S, Rancan F, Blume-Peytavi U, Schäfer-Korting M, Schindler A, Rühl E, Stahl Skov P, Church M, Hedtrich S, Kleuser B, Bodmeier R, Vogt A 2016. Ethyl cellulose nanocarriers and nanocrystals differentially deliver dexamethasone into intact, tape-stripped or sodium lauryl sulfate-exposed ex vivohuman skin -assessment by intradermal microdialysis and extraction from the different skin layers. Accepted for publication in: J Control Release , DOI 10.1016/j.jconrel.2016.07.009