Teilprojekte

Teilprojekte des SFB 1112


Projektbereich A: Synthese, Wirkstoffaufnahme und Markierung von Nanocarriern
A01 R. Bodmeier (Pharmazeutische Technologie, Institut für Pharmazie, FU Berlin) Development of "smartNLC" and "ARTcrystals" for dermal application of drugs
A02 R. Haag (Institut für Chemie und Biochemie, FU Berlin) Polymer architectures with responsive nanocarriers for drug delivery
A03 A. Lendlein/A. Neffe (Inst. für Biomaterialforschung, Helmholtz Zentrum Geesthacht, Teltow) Drug releasing, biodegradable depsipeptide nanoparticles for dermal treatments
A04  R. Haag/M. Calderón (Institut für Chemie und Biochemie, FU Berlin) Development of pH-cleavable and thermoresponsive nanogels as nanocarriers for the transdermal triggered release of drugs

Projektbereich B: Physikalische Diagnostik und numerische Modellierung
B01 M. Meinke/R. Bittl (Dermatologie, Charité Berlin / (Fachbereich Physik, FU Berlin) EPR spectroscopic investigations on drug delivery and release of nanocarriers into cutaneous cells and excised skin
B02 E. Rühl (Institut für Chemie und Biochemie, FU Berlin) Spatially and temporally resolved studies on the transport of nanocarriers and drug release in cells and skin
B03 U. Alexiev (Fachbereich Physik, FU Berlin) Characterization of transport and release properties of responsive nanocarriers by fluorescence  spectroscopy and localization microscopy
B04 R. Netz (Fachbereich Physik, FU Berlin) Multiscale models for carrier-assisted drug transport through skin

Projektbereich C: Nanopharmakologie und Dermatologie
C02 M. Schäfer-Korting/S. Hedtrich, geb. Küchler (Institut für Pharmazie, FU Berlin) In vitro disease models – test platform for the investigation of nanocarrier  related transport, activity, and toxicity of drugs
C03 L. Mundhenk/A. Gruber (Fachbereich Veterinärmedizin, FU Berlin) Nanocarriers in the skin of mouse models: Penetration, effects of barrier   dysfunctions in diseased skin and improved targeting of inflammation
C04 A. Vogt/U. Blume-Peytavi (Dermatologie, Charité Berlin) Ex vivo human skin: Impact of skin barrier function and the presence of hair  follicles on nanocarrier-based anti-inflammatory therapy
C05 J. Lademann (Dermatologie, Charité Berlin) Dermal trigger parameters for drug release from nanocarriers

Zentralprojekte
Z01 B. Kleuser/N. Ma/M. Schäfer-Korting (Institut für Ernährungswissenschaften, U Potsdam/Inst. für Biomaterialforschung, Helmholtz Zentrum Geesthacht (Teltow)/ Institut für Pharmazie, FU Berlin) Toxicity of native and drug-loaded nanocarriers
MGK E. Rühl (Institut für Chemie und Biochemie, FU Berlin) Integrated Research Training Group “Nanocarriers"
Z02 E. Rühl (Institut für Chemie und Biochemie, FU Berlin) Central tasks - CRC Headquarter and administration